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SP- and CGRP-immunoreactive axons differ in their ability to reinnervate the skin of the rat tail
E M McLachlan1, J R Keast, M Bauer
1Department of Physiology and Pharmacology, University of Queensland, Australia.
Neuroscience Letters
|August 1, 1994
Abstract:
The reinnervation of cutaneous targets was studied in the rat tail after proximal lesions of all collector nerves. The distribution of immunofluorescent nerve fibres stained for calcitonin-gene-related peptide (CGRP) and substance P (SP) was examined after 110-210 days. Targets at all sites were reinnervated by CGRP-immunoreactive (IR) fibres. However, SP-IR terminals were rare, particularly distally, despite staining within subdermal nerve trunks.