[Current tasks of psychopharmacology]

The basic principle of psychopharmacology--is its impact on the psychopathological syndrome, having in view its specificity, expressivity of negative disturbances, nosological entity. One of the approaches to the selection of adequate psychopharmacotherapy may be the concept of comorbidity of disturbances, determining the structure of the syndrome and perspectives of its impact. With this in view, the structure of some syndromes may be considered not as a complex of closely interrelated disturbances, but as states stemming from relatively independent pathological disturbances, connected by probable relations. The problem of differentiated psychopharmacotherapy in line with the phenomenon of comorbidity at the level of symptom-syndrome, psychopathological personality disturbances (including negative ones), may have a practical as well as a theoretical significance. An analysis of comorbid connections determines as well the selection of preventive drugs in the prophylaxis of relapses of psychoses. An eventual study of all sides of this problem has its goal to define the spectre of action of the already known drugs and new psychopharmacological preparations, a deeper understanding of psychopathology and the clinical state being under the impact of psychopharmacological therapy, a transition from an extensive understanding of a wide range of questions of psychopharmacology to an intensive study of separate facets of the problem, which seems to be most perspective.