[Interdependence of the immune system and structure of extracellular matrix proteins]

The major proteins from plasma and extracellular matrices (ECM) are described. The interaction of lymphoid cells with their microenvironment is critical for their growth and function. The interaction with ECM may play a significant role in defining the biological properties of many cells. ECM form a network of bioactive proteins, that is being linked with an increasing number of processes, including antigen-independent activation, proliferation, homing and cell migration. Some aspects of the participation of the extracellular matrix in the language of intracellular communication is discussed.