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Tumour vasculature--a potential therapeutic target
C T Baillie1, M C Winslet, N J Bradley
1University Department of Surgery, Royal Free Hospital and School of Medicine, London, UK.
British Journal of Cancer
|August 1, 1995
Abstract:
The tumour vasculature is vital for the establishment, growth and metastasis of solid tumours. Its physiological properties limit the effectiveness of conventional anti-cancer strategies. Therapeutic approaches directed at the tumour vasculature are reviewed, suggesting the potential of anti-angiogenesis and the targeting of vascular proliferation antigens as cancer treatments.