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Updated: Jun 30, 2026

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

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Mortality from benign prostatic hyperplasia: worldwide trends 1950-92

C La Vecchia¹, F Levi, F Lucchini

¹Istituto di Ricerche Farmacologiche, Mario Negri, Milano, Italy.

Journal of Epidemiology and Community Health

|August 1, 1995

Summary

This summary is machine-generated.

Worldwide mortality from benign prostatic hyperplasia (BPH) has significantly decreased over four decades due to improved treatments. However, some regions still report high BPH death rates, indicating a need for continued medical advancements.

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Area of Science:

Gerontology and Geriatric Medicine
Urology
Public Health and Epidemiology

Background:

Benign prostatic hyperplasia (BPH) is a common condition in aging men.
Understanding global mortality trends in BPH is crucial for public health initiatives.
Historical data on BPH mortality provides insights into the impact of medical interventions.

Purpose of the Study:

To systematically analyze worldwide mortality trends associated with benign prostatic hyperplasia (BPH).
To examine changes in BPH mortality rates over a four-decade period (1950-1992).
To identify geographical variations in BPH mortality trends.

Main Methods:

Descriptive analysis of age-adjusted mortality rates for BPH.
Data sourced from official death certifications via the World Health Organization database.
Analysis covered 41 countries across five continents from 1950 to 1992.

Main Results:

Significant decline in BPH mortality observed globally, exceeding 90-95% in Western Europe by 1990.
Mortality rates in Western Europe dropped from over 20/100,000 in the 1950s to 0.5-1.5/100,000 by the early 1980s.
Similar reductions noted in North America, Asia, and Oceania; smaller decreases seen in Eastern Europe and Latin America.

Conclusions:

Therapeutic advancements, including surgical and medical treatments, are strongly linked to reduced BPH mortality.
Widespread adoption of less invasive procedures like transurethral prostatectomy has likely contributed to favorable outcomes.
Persistent high BPH mortality rates in certain areas of Western Europe and South America warrant further investigation and intervention.