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[Continuous subcutaneous infusion of opioids in cancer patients]
J M Galamba1, A K Olsen, M E Crawford
1Tvaerfagligt smertecenter, Bispebjerg Hospital.
Ugeskrift for Laeger
|July 17, 1995
Abstract:
This review article describes pharmacokinetics, pharmaco-dynamics, side effects and the practical use of continuous subcutaneous infusion of opioids in cancer patients with pain. Clinical studies have shown that the analgesic effects of continuous subcutaneous infusion of morphine are comparable to continuous intravenous morphine, and that the treatment modality is associated with a low frequency of side-effects and complications. Continuous subcutaneous infusions of morphine are therefore recommended as the treatment of choice for cancer patients with pain, when oral analgesic treatment is no longer possible.