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Clinical detection of unilateral keratoconus
L R Lee1, L W Hirst, G Readshaw
1Department of Surgery, Princess Alexandra Hospital, Woolloongabba, Qld.
Purpose:
To determine the incidence of true unilateral keratoconus on the basis of computerised corneal topography in a group with clinically diagnosed unilateral keratoconus.
Methods:
Retrospective review of 295 patients with keratoconus identified 51 patients with a provisional diagnosis of unilateral keratoconus. Thirty-one of these patients were re-examined clinically and 21 patients met the criteria for a clinical diagnosis of unilateral keratoconus. Computerised corneal topographic analysis (Tomey TMS) was then performed.
Results:
In a group of 21 patients with clinically diagnosed unilateral keratoconus, computerised corneal topographic analysis identified 14 (67%) patients with bilateral keratoconus and seven (33%) patients with true unilateral keratoconus. Contact lens wear had no significant influence (P=0.76) on the topographical diagnosis of keratoconus in the clinically unaffected fellow eye. The estimated incidence of true unilateral keratoconus in the cohort of 295 patients was 4%.
Conclusions:
Computerised corneal topography improves sensitivity in detection of true unilateral keratoconus.