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Related Experiment Videos

Zinc, human diseases and aging

N Fabris1, E Mocchegiani

  • 1Research Department, Italian National Research Center on Aging (I.N.R.C.A.), Ancona.

Aging (Milan, Italy)
|April 1, 1995
PubMed
Summary
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Zinc is an essential trace element vital for over 200 enzymes and cellular functions. Supplementation is effective for various conditions, highlighting zinc

Area of Science:

  • Biochemistry
  • Human Physiology
  • Nutritional Science

Background:

  • Zinc is a critical trace element, indispensable for numerous biological functions.
  • It acts as a cofactor for over 200 enzymes and is integral to protein structure, hormone function, and gene regulation.
  • Zinc's role extends from embryonic development to aging, impacting cell division, differentiation, and biomembrane integrity.

Purpose of the Study:

  • To elucidate the multifaceted biological roles of zinc in the human body.
  • To explain the diverse clinical manifestations of zinc deficiency and its impact on health.
  • To emphasize the therapeutic potential of zinc supplementation in various pathologies and aging processes.

Main Methods:

  • Literature review of zinc's biochemical and physiological functions.

Related Experiment Videos

  • Analysis of clinical and laboratory findings related to zinc bioavailability.
  • Synthesis of experimental data on zinc's role in aging and associated diseases.

    • Main Results:

    • Zinc is crucial for enzymatic activity, cell division, gene transcription, and overall organismal function.
    • Altered zinc levels are linked to a wide array of human pathologies.
    • Zinc supplementation demonstrates efficacy in managing these conditions, positioning it as a therapeutic agent.

    Conclusions:

    • Zinc is fundamental to maintaining health throughout the lifespan.
    • Dysregulation of zinc homeostasis contributes to disease development.
    • Targeted zinc supplementation is a valuable therapeutic strategy, particularly concerning age-related diseases and the aging process.