[The histological, histochemical and ultrastructural characteristics of induced ectopic chondrogenesis]

Implantation of the chondrogenesis inductor (demineralized osseous powder) into the subcutaneous fat in the area of the rat lower extremity muscles caused clear histological, histochemical and ultrastructural manifestations of ectopic chondrogenesis in certain zones of close contact with the inductor. Fibrogenic mesenchyme cells and fibroblasts proliferating by the glottis between the 6 th postoperative day and forming the bands, invading the glottis between the inductor granules were probably the object of chondrogenic transformation. Stages of these cells chondrogenic differentiation, hyaline cartilage forming and manifestations of its following ossification were followed up. The process of the induced ectopic chondrogenesis after fibrogenic cells transformation into chondroblasts passes the stages similar to that of the cartilage embryogenesis.