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[Changes in the tissues of a revascularized transplant of small intestine in the dog under different operating
Iu P Khussar1, O V Milenin, E O Tiunder
1Department of Histology and Faculty Surgery, University of Tartu.
Abstract:
Histomorphological changes of revascularized autotransplant were studied in 34 dogs in different conditions of the operation. It was established that revascularization is necessary for transplantation. Organ disintegrates without vascular peduncle. Prolonged operative ischemia (up to 3 hrs) of the transplant causes its essential alternative and destructive changes up to the complete disintegration of part of the villi. Autotransplant of the small intestine preserves tissue and cell composition on the neck for a long period (more than a year) and may be used in replacing operations on the esophagus. However, complete organotypic and tissue restoration of the structure does not occur. Villi disappear, crypt epithelium forms structures resembling terminal regions of cardial glands, simple intestinal epithelium is replaced with the stratified one.