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Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
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The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
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The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
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The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

[Enteropathogenic agents isolated in persistent diarrhoea].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·1996
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[Esophageal stenosis in children. Complications of esophageal dilatations (Part III)].

Acta gastroenterologica Latinoamericana·1996
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[Study of intestinal microflora in children with acute and persistent diarrhea].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·1995
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[Esophageal stenosis in children. Etiology, pathogenesis, and diagnosis (part I)].

Acta gastroenterologica Latinoamericana·1995
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[Treatment of esophageal stenosis with Savary-Gilliard balloons in children].

G.E.N·1995
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[Persistent diarrhea].

G.E.N·1995

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Updated: May 6, 2026

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
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[Intestinal microflora in children with acute and persistent diarrhea]

Y García Cristia1, T Fragoso Arbelo, M Valdés-Dapena Vivanca

  • 1Hospital Pediátrico Docente Juan Manuel Marquez, Servicio de Gastroenterología.

G.E.N
|October 1, 1994
PubMed
Summary

Altered duodenal microflora, including bacterial overgrowth, is linked to persistent diarrhea in infants. Microbiological analysis of duodenal content helps identify risk factors influencing diarrhea duration.

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Area of Science:

  • Gastroenterology
  • Microbiology
  • Pediatrics

Context:

  • Persistent diarrhea in infants often has an unidentified, multifactorial etiology.
  • Understanding the role of enteric microflora in diarrhea duration is crucial.

Purpose:

  • To investigate if alterations in enteric microflora are a risk factor for persistent diarrhea in infants.
  • To correlate duodenal microflora with nutritional status and prior antibiotic use.

Summary:

  • Studied 30 infants with acute diarrhea and 30 with persistent diarrhea.
  • Analyzed duodenal content for enteric microorganisms, anaerobes, and Candida.
  • Found bacterial overgrowth and altered duodenal flora in both groups, indicating a role in diarrhea persistence.

Impact:

  • Highlights the significance of duodenal microflora analysis in diagnosing and managing persistent diarrhea.
  • Suggests potential therapeutic targets for restoring gut health in affected infants.