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Subendometrial myometrial contractions associated with transcervical chorionic villous sampling
S Degani1, A Gruber, K de Vries
1Department of Obstetrics and Gynecology, Bnai-Zion Medical Center, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
Gynecologic and Obstetric Investigation
|January 1, 1995
Summary
Chorionic villus sampling (CVS) significantly increases myometrial contractions, with 78% of patients showing heightened uterine activity post-procedure. This uterine activity correlates with cramping but not vaginal bleeding.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Medicine
- Medical Imaging
Background:
- Prenatal diagnosis is crucial for identifying fetal abnormalities.
- Chorionic villus sampling (CVS) is a common invasive diagnostic procedure.
- Uterine activity during pregnancy can impact diagnostic procedures and outcomes.
Purpose of the Study:
- To investigate the effect of chorionic villus sampling (CVS) on myometrial contractions.
- To assess the correlation between myometrial activity and patient-reported symptoms like cramping and bleeding.
- To evaluate the diagnostic utility of transvaginal ultrasound in detecting uterine activity post-CVS.
Main Methods:
- Transvaginal ultrasound was used to monitor myometrial contractions in 32 patients undergoing CVS.
- Uterine activity was assessed before and immediately after the chorionic villus sampling procedure.
- Correlation analysis was performed between ultrasound findings and reported symptoms.
Main Results:
- Increased myometrial activity was observed in 78% of patients post-CVS.
- Mean frequency of contractions increased 3.5-fold and amplitude 4.2-fold.
- Myometrial contractions detected by ultrasound showed 70% sensitivity for predicting cramping, but only 31% for vaginal bleeding.
Conclusions:
- Chorionic villus sampling significantly elevates myometrial contractions.
- Ultrasonographically detected uterine activity is a sensitive indicator of post-CVS cramping.
- Further research is needed to understand the prognostic implications of this increased uterine activity.