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Parapharyngeal space neoplasms

K V Hughes1, K D Olsen, T V McCaffrey

  • 1Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota 55905, USA.

Head & Neck
|March 1, 1995
PubMed
Summary

Primary parapharyngeal space neoplasms are rare, with benign tumors like pleomorphic adenoma being most common. Malignant parapharyngeal tumors have a poor prognosis, emphasizing the need for effective surgical approaches.

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Area of Science:

  • Otolaryngology
  • Head and Neck Surgery
  • Surgical Oncology

Background:

  • Primary parapharyngeal space neoplasms are uncommon tumors.
  • Tumor characteristics and outcomes show variability in existing literature.
  • This study reviews surgical treatment of 172 patients from 1960-1990.

Purpose of the Study:

  • To analyze tumor distribution and long-term outcomes of primary parapharyngeal space neoplasms.
  • To evaluate the effectiveness of surgical management for these rare tumors.

Main Methods:

  • Retrospective review of 172 surgically treated patients with primary parapharyngeal space neoplasms.
  • The transparotid-cervical surgical approach was predominantly utilized.
  • Diagnostic tools included high-resolution computed tomography and magnetic resonance imaging.

Main Results:

  • 80% of tumors were benign, with pleomorphic adenoma being the most frequent (40%).
  • Malignant tumors constituted 20% of cases, with a high mortality rate (89% likely to die of disease).
  • The transparotid-cervical approach was effective; mandibulotomy was reserved for specific complex cases.

Conclusions:

  • The transparotid-cervical approach is the preferred surgical method for parapharyngeal tumors.
  • Recurrence of pleomorphic adenoma is low (4%), but recurrent malignant disease is often fatal.
  • Perioperative mortality was zero, with morbidity mainly related to cranial nerve issues.

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