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Related Experiment Videos

Pulmonary zygomycosis: CT appearance

D A Jamadar1, E A Kazerooni, B D Daly

  • 1Department of Radiology, University of Michigan Hospital, Ann Arbor 48109-0326, USA.

Journal of Computer Assisted Tomography
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

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Pulmonary zygomycosis (mucormycosis) CT findings include posterior upper lobe nodules and consolidations. This opportunistic infection requires prompt recognition in immunocompromised patients.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Pulmonary zygomycosis (mucormycosis) is a rare, opportunistic fungal infection.
  • It predominantly affects immunocompromised individuals, posing a diagnostic challenge.

Purpose of the Study:

  • To characterize the computed tomography (CT) imaging features of pulmonary zygomycosis.
  • To correlate CT findings with clinical presentation and outcomes.

Main Methods:

  • Retrospective review of CT scans from eight patients diagnosed with pulmonary zygomycosis.
  • Assessment of lesion characteristics, including size, number, location, and associated findings like pleural effusion and necrosis.

Main Results:

  • Common CT findings included posterior upper lobe nodules and wedge-shaped consolidations.

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  • Other observed features were pleural effusion, halo sign, central low attenuation, and cavitation.
  • Less common presentations included endobronchial disease and complications like spinal invasion and pseudoaneurysms.
  • Conclusions:

    • Posterior upper lobe nodules or consolidations on CT should raise suspicion for pulmonary zygomycosis in at-risk patients.
    • Endobronchial zygomycosis represents a less frequent manifestation of the disease.