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Tripe palms: a cutaneous marker of internal malignancy
L Requena1, A Aguilar, G Renedo
1Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
The Journal of Dermatology
|July 1, 1995
Summary
Tripe palms, a skin condition, can signal internal cancers like ovarian carcinoma. Surgical removal of the cancer led to the complete disappearance of the tripe palms.
Area of Science:
- Dermatology
- Oncology
Background:
- Tripe palms is a rare paraneoplastic sign linked to internal malignancies, particularly lung and stomach cancers.
- This condition presents as a distinct rugose thickening of the palms, accentuating dermatoglyphic ridges.
Observation:
- A case study details a patient with ovarian carcinoma presenting with prominent tripe palms, especially on the fingertips.
- The patient also exhibited acanthosis nigricans in the axillae and groin, while the soles remained unaffected.
Findings:
- Histopathology of palmar lesions revealed epidermal changes including hyperkeratosis, acanthosis, and papillomatosis.
- Complete regression of the cutaneous lesions was observed post-excision of the ovarian carcinoma.
Implications:
- This case highlights the association between tripe palms and ovarian cancer, expanding the known spectrum of associated malignancies.
- The findings underscore the importance of investigating paraneoplastic dermatologic signs for underlying internal cancers.
- Successful treatment of the primary malignancy resulted in the resolution of the associated tripe palms, suggesting a direct causal link.