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Related Experiment Videos

[Radiologic visibility of breast fibroadenomas]

J Pierart1, R Burmeister, J Steinberg

  • 1Departamento de Cirugía, Universidad de Concepción, Chile.

Revista Medica De Chile
|February 1, 1995
PubMed
Summary

Some fibroadenomas are not visible on mammograms, particularly in younger women or those with fibrocystic disease. This lack of visibility may be linked to tumor composition, specifically sodium chloride and potassium chloride content.

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Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Mammary fibroadenomas often appear clinically similar.
  • Mammographic visibility of fibroadenomas can vary, potentially due to glandular density or tumor characteristics.

Purpose of the Study:

  • To investigate the factors contributing to the mammographic invisibility of fibroadenomas.
  • To determine if glandular density or intrinsic tumor properties influence mammographic detection.

Main Methods:

  • Correlation of mammographic visibility with patient age, fibrocystic disease, and histological type in 201 cases.
  • X-ray analysis of excised fibroadenoma samples.
  • X-ray diffraction analysis of calcined tumor ashes.

Main Results:

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  • Twenty-two percent of fibroadenomas were not mammographically visible, with higher rates in intracanalicular types, younger women, and those with fibrocystic disease.
  • Sixteen percent of excised and sliced tumors remained invisible on X-ray.
  • X-ray diffraction revealed differences in NaCl and KCl content between visible and invisible tumors.

Conclusions:

  • Fibroadenoma mammographic invisibility is multifactorial, influenced by patient demographics, disease presence, and tumor composition.
  • Tumor content, particularly NaCl and KCl, may play a role in mammographic detection of fibroadenomas.