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[Rheumatic involvement in Hansen's disease]

W Cossermelli-Messina1, W Cossermelli

  • 1Disciplina de Reumatologia/Laboratório de Investigação em Reumatologia, Faculdade de Medicina, Universidade de São Paulo.

Revista Do Hospital Das Clinicas
|March 1, 1995
PubMed
Summary

Hansen's disease (leprosy) can cause joint issues mimicking rheumatic diseases. Early diagnosis is crucial to prevent severe complications and transmission.

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Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Immunology

Context:

  • Hansen's disease (leprosy) classically presents with neurogenic arthropathy and osteitis.
  • Inflammatory arthritis and extra-articular manifestations in leprosy can resemble connective tissue diseases.
  • Distinguishing rheumatic syndromes from hanseniasis is clinically significant.

Purpose:

  • To highlight the diverse articular and extra-articular manifestations of Hansen's disease.
  • To emphasize the inflammatory and rheumatoid-like arthritic presentations in leprosy patients.
  • To underscore the importance of differential diagnosis between rheumatic conditions and hanseniasis.

Summary:

  • Hansen's disease presents with classical Charcot's arthropathy, osteitis, and osteoarthritis.
  • Inflammatory mechanisms in leprosy can lead to rheumatoid-like arthritis, supported by clinical, biopsy, and lab data.
  • Extra-articular symptoms of Hansen's disease can mimic connective tissue disorders.

Impact:

  • Facilitates earlier identification of Hansen's disease, preventing severe sequelae.
  • Aids in preventing the transmission of leprosy through timely diagnosis and treatment.
  • Improves patient outcomes by differentiating leprosy from other rheumatic conditions.

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