[Primary intracranial and intraspinal neoplasms in Denmark 1943-1987]

This is a descriptive study of primary intracranial and intraspinal tumours notified to the national Danish Cancer Registry during the years 1943-1987. A total of 19,317 cases of benign and malignant neoplasms were included over these 45 years with a doubling of the age-standardized incidence rates for both men and women from start till end of the registration period. The trend was mainly explained by markedly increasing rates in the age groups 60 years or above at diagnosis. Approximately some 74% of tumours were derived from the brain tissues and 19% from the intracranial and intraspinal meninges. Meningiomas predominate among women with a male:female ratio of 0.5, while tumours of the brain tissues predominate among men (ratio 1.3). Meningiomas are more frequently encountered as a chance finding at autopsy compared to other types of intracranial and intraspinal tumours. The above-mentioned increase in age-specific incidence is due mainly to improved diagnostic capabilities over the period and a subsequent decrease in the underreporting of these tumour types.