[Primary cutaneous malignant lymphoma -- Sézary syndrome]

The paper presents a girl with cutaneous lymphoma. The onset of the illness was two years ago, and followed by cutaneous lesions, typical Mycosis fungoides and Sêzary's syndrome. After a year, the neoplastic cells penetrated into the peripheral blood, and the development of Sézary's variant of Mycosis fungoidses, was shown. The clinical development of the disease, and the application of hystopathological and laboratory investigations, proved that it was the Sézary's syndrome. When the adequete cytostatic therapy, and radiotherapy, was applied, according to the protocol for curing the malignant non Hodgkin lymphoma, the clinical and haematological remission of disease was performed.