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Phenotype and cancer risk of various polyposis syndromes
F M Giardiello1, J G Offerhaus
1Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.
European Journal of Cancer (Oxford, England : 1990)
|July 1, 1995
Abstract:
The gastrointestinal polyposis syndromes are disorders with multiple intestinal polyps. Three of these disorders, familial adenomatous polyposis, Peutz-Jeghers syndrome and juvenile polyposis are associated with increased risk of colorectal as well as extracolonic cancers. A description of the phenotype and associated cancer risk is provided for each.