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Percutaneous thoracic duct cannulation: feasibility study in swine
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
Summary
Percutaneous thoracic duct (TD) catheterization is feasible in pigs. This safe and repeatable technique shows promise for organ transplantation and treating TD lacerations.
Area of Science:
- Veterinary medicine
- Interventional radiology
- Anatomy
Background:
- The thoracic duct (TD) is the largest lymphatic vessel in the body.
- Accurate catheterization of the TD is crucial for various medical interventions.
- Previous methods for TD access may have limitations.
Purpose of the Study:
- To evaluate the feasibility of percutaneous catheterization of the thoracic duct (TD) in a swine model.
- To establish a safe and repeatable technique for TD access.
Main Methods:
- Pedal lymphography was used to opacify the cisterna chyli (CC).
- Transabdominal puncture of the CC was performed with a 21-gauge needle.
- Catheterization of the TD was achieved using antegrade and retrograde techniques via a guide wire.
Main Results:
- Successful TD catheterization was achieved in 13 out of 15 pigs (87%).
- Both antegrade (n=4) and antegrade-retrograde (n=9) approaches were successful.
- No acute complications were observed during the procedures.
Conclusions:
- Percutaneous transabdominal TD catheterization is a feasible, safe, and repeatable procedure in swine.
- This technique holds potential for clinical applications in organ transplantation.
- The method may also be beneficial for managing TD lacerations.