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Updated: Aug 17, 2026

Visualization of the Embryonic Nervous System in Whole-mount Drosophila Embryos
Published on: December 11, 2010
Determination events in the nervous system of the vertebrate embryo
1Department of Molecular Biology, Princeton University, New Jersey 08544, USA.
Abstract:
Molecular and functional data suggest that the regionalization of the caudal portion of the vertebrate embryonic brain (hindbrain) is set up through a process of segmentation. In contrast, the more rostrally located met-mesencephalic domain (mid-hindbrain junction) appears to follow a mode of specification that relies on long-range inducing and organizing activities originating from the central region of the domain. Recent studies addressing this mode of anterior/posterior determination point to Wnt-1 as a key player in this process.
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