[Mitotic regimen of non-Hodgkin's lymphoma]

The mitotic regimen of non-Hodgkin's lymphomas (n = 86) and of reactive follicular hyperplasia (n = 14) has been studied. A correlation between the parameters of mitotic regimen and morphologic degradation of malignant lymphomas has been revealed. Blastic forms of lymphomas were found to be characterized by the highest mitotic activity with a greater number and variety of forms of pathologic mitoses (p < 0.001). The frequency of mitoses in lymphomas of low malignancy was found to be reliably reduced in comparison with that in follicular hyperplasia (p < 0.01). The results of assessing the mitotic regimen are recommended to be used for the differential diagnosis and subclassification of non-Hodgkin's lymphomas.