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High-resolution structural studies of the factor XIIIa crosslinking site and the first type 1 module of fibronectin
Nature Structural Biology
|November 1, 1995
Abstract:
The N-terminal domain of fibronectin undergoes factor XIIIa-catalysed crosslinking to fibrin, bacteria and collagen. The reactive glutamine residue is in an extended, random coil 'tail' of about 18 residues that would be accessible for crosslinking.