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Interferons: their role in clinical practice
1Division of Allergy and Clinical Immunology, Harbor-UCLA Medical Center, Torrance, USA.
Objective:
To describe the current indications and side effects of Interferons in the treatment of human disease together with sufficient background information to understand the rationale for their use.
Data Sources:
Literature searches on interferons extended back to the time of their discovery. Citations were limited to English and human aspects. Reference lists from recent reviews were also consulted.
Study Selection:
Reviews of fundamental mechanisms were selected together with studies of individual clinical trials and anecdotal experiences with human use of interferons.
Conclusions:
Interferons are accepted therapy for a number of conditions. Their range of therapeutic uses will undoubtedly increase as further knowledge is obtained.
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