Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lymphangiosarcoma following mastectomy

N J Stewart1, D J Pritchard, A G Nascimento

  • 1Department of Orthopedics, Mayo Clinic, Rochester, MN 55905, USA.

Clinical Orthopaedics and Related Research
|November 1, 1995
PubMed
Summary

Stewart-Treves syndrome, a rare lymphangiosarcoma, can develop years after breast cancer mastectomy. Early recognition and surgical intervention are crucial for improving survival chances in these challenging cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Four-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

[Application value of DNA damage repair variants in adjuvant therapy of triple negative breast cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2023
Same author

Fiber reinforced hydrated networks recapitulate the poroelastic mechanics of articular cartilage.

Acta biomaterialia·2023
Same author

EXPERIMENTAL MANIPULATION OF ALTERNATIVE PATHWAYS OF DIFFERENTIATION IN CULTURES OF EMBRYONIC CHICK NEURAL RETINA.

Development, growth & differentiation·2023
Same author

Corrigendum to "SELNET clinical practice guidelines for soft tissue sarcoma and GIST" [Cancer Treat. Rev. 102 (2021) 102312].

Cancer treatment reviews·2023
Same author

Corrigendum to "SELNET clinical practice guidelines for bone sarcoma" Critical reviews in oncology/hematology, vol. 174 (2022), 1-10.

Critical reviews in oncology/hematology·2022

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Stewart-Treves syndrome is a rare complication following mastectomy for breast cancer.
  • It involves the development of lymphangiosarcoma in the upper extremity.
  • This condition typically manifests years after the initial breast cancer treatment.

Purpose of the Study:

  • To review cases of lymphangiosarcoma of the upper extremity after mastectomy for breast cancer.
  • To analyze the clinical presentation, treatment, and outcomes of Stewart-Treves syndrome.
  • To identify factors associated with long-term survival.

Main Methods:

  • Retrospective review of 16 patients diagnosed with lymphangiosarcoma of the upper extremity between 1970 and 1992.
  • Analysis of patient data including time from breast cancer diagnosis, presenting signs, surgical treatment, recurrence, and metastasis.

Related Experiment Videos

  • Evaluation of survival rates based on treatment modality.

    • Main Results:

    • Lymphangiosarcoma diagnosis occurred an average of 10.6 years post-mastectomy.
    • Common presenting signs included bruising and swelling.
    • High rates of local recurrence (11/16) and metastasis (11/16) were observed.
    • Forequarter amputation and wide excision with grafting were primary surgical treatments.
    • Two long-term survivors were identified, suggesting potential benefit from aggressive surgical management.

    Conclusions:

    • Stewart-Treves syndrome presents a significant challenge with high recurrence and metastasis rates.
    • Early detection and prompt surgical treatment, such as forequarter amputation or wide excision, appear critical for long-term survival.
    • Further research into preventative strategies and adjuvant therapies may be warranted.