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Inflammatory bronchial polyps associated with asthma: resolution with inhaled corticosteroid
The European Respiratory Journal
|July 1, 1995
Summary
Inhaled corticosteroids effectively treated inflammatory bronchial polyps in a patient with asthma. This treatment led to polyp regression and asthma symptom relief, suggesting a potential therapeutic option.
Area of Science:
- Pulmonology
- Allergy and Immunology
Background:
- Inflammatory polyps in the bronchi can cause respiratory symptoms.
- Asthma is a common comorbidity associated with eosinophilic airway inflammation.
Observation:
- A 50-year-old male presented with cough and sputum, revealing an endobronchial polyp.
- Six years later, the patient developed asthma, and a second polyp was identified.
- The initial polyp remained unchanged endoscopically and histologically.
Findings:
- Inhaled beclomethasone dipropionate (200 micrograms b.i.d.) resolved asthma symptoms.
- Both bronchial polyps regressed and disappeared after one year of inhaled corticosteroid treatment.
Implications:
- Inhaled corticosteroids offer a noninvasive and safe treatment for inflammatory bronchial polyps.
- This approach is particularly promising for patients with coexisting asthma or small, non-urgent polyps.