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Ovarian volume: a novel outcome predictor for assisted reproduction
C H Syrop1, A Willhoite, B J Van Voorhis
1Department of Obstetrics and Gynecology, University of Iowa College of Medicine, Iowa City 52242-1080, USA.
Objective:
To determine the potential of ovarian volume as a predictor of assisted reproduction outcomes.
Design:
Retrospective chart review.
Setting:
University-based assisted reproduction program.
Patients:
One hundred eighty-eight women initiating their first cycle of assisted reproduction.
Interventions:
None.
Main Outcome Measures:
Pretreatment transvaginal ultrasound ovarian measurements were compared with subsequent ovulation induction parameters (peak E2, numbers of oocytes, and embryos) and cycle outcome (cancellation and pregnancy).
Result:
Total ovarian volume and volume of the smallest ovary were significant variables predicting peak E2 and numbers of oocytes and embryos. Total ovarian volume was a predictor of cycle cancellation and volume of the smallest ovary a predictor of clinical pregnancy. Large ovarian volumes are associated with good assisted reproductive technology outcomes whereas small ovarian volumes are associated with poor outcomes.
Conclusion:
Beyond maternal age, total ovarian volume, and volume of the smallest ovary are significant predictors of the success of assisted reproductive techniques.