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Published on: November 3, 2016
Myotatic reflex responses of non-disabled children and children with spastic cerebral palsy
1Physical Therapy Department, University of Montana, Missoula 59812, USA.
Insights
Children with cerebral palsy (CP) show persistent reflex irradiation beyond age two, unlike typically developing children. This suggests underlying neural differences in motor control for individuals with CP.
Area of Science:
- Neuroscience
- Developmental Pediatrics
- Biomedical Engineering
Background:
- Myotatic reflexes are fundamental to motor control.
- Cerebral palsy (CP) affects motor development, but reflex patterns are not fully understood.
- Reflex irradiation, the spread of reflex activity, is a key area of investigation.
Purpose of the Study:
- To compare myotatic reflex responses in infants and children with and without cerebral palsy.
- To investigate the developmental trajectory of reflex irradiation in these groups.
- To explore potential neural mechanisms underlying differences in reflex responses in CP.
Main Methods:
- Surface electromyography (EMG) was utilized to measure muscle activity.
- Patellar and Achilles tendon taps were used to elicit myotatic reflexes.
- Participants included normally developing infants/children and those with cerebral palsy.
Main Results:
- Reflex irradiation was observed in both groups under two years of age.
- Infants with CP exhibited higher muscle amplitude upon direct stimulation.
- After age two, reflex irradiation persisted in children with CP but diminished in non-disabled children.
Conclusions:
- Persistent reflex irradiation in children with CP suggests atypical neural pathway development.
- Findings may indicate underlying neural mechanisms contributing to motor impairments in CP.
- Understanding these reflex patterns has potential clinical relevance for CP management.
Abstract:
Surface electromyography (EMG) was used to examine lower-extremity myotatic reflex responses following patellar or Achilles tendon taps to normally developing, non-disabled infants and to individuals with cerebral palsy (CP). Reflex irradiation was present in non-disabled infants and infants with CP under two years of age. The only significant differences in myotatic reflex responses between the two groups at this age was the higher amplitude of the directly stimulated muscle of children with CP. After two years the amplitude did not differ between groups. Reflex irradiation, however, was greatly reduced in the non-disabled children but not in the children with cerebral palsy. These findings and those of non-human animal studies indicate the possible neural mechanisms that underlie reflex irradiation of individuals with CP. The potential clinical relevance of these findings is discussed.
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