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[Spherulocytosis (myospherulosis) of the paranasal sinuses]

G S Godbersen1, J Kleeberg, J Lüttges

  • 1Klinik für Hals-, Nasen-, Ohrenheilkunde, Universität Kiel.

HNO
|September 1, 1995
PubMed

Insights

Spherulocytosis, a condition caused by lipid emulsions in wounds, can impede healing, particularly after paranasal sinus surgery. Avoidance of lipid-based nasal packs post-surgery is recommended to prevent this foreign-body reaction.

Area of Science:

  • Medical Science
  • Pathology

Background:

  • Spherulocytosis (myospherulosis) arises from the interaction of lipid-based materials with blood.
  • It is often associated with the application of lipid-containing ointments or antibiotic preparations to wounds.

Observation:

  • This condition triggers a foreign-body reaction, manifesting as granulation tissue.
  • Symptomatic development occurs in closed wounds or cavities like the middle ear and paranasal sinuses.

Findings:

  • Poor healing following paranasal sinus surgery may be attributed to spherulocytosis.
  • Cases at University Hospital in Kiel indicated postoperative nasal packs sensitized sinus mucosa, leading to this complication.

Implications:

  • The findings suggest that nasal ointment packs should be avoided in paranasal sinus surgery.
  • This recommendation aims to prevent spherulocytosis and improve surgical outcomes.

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