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Cutaneous telangiectases in neonatal lupus erythematosus
C M Thornton1, L F Eichenfield, E A Shinall
1Division of Dermatology, University of California, San Diego, USA.
Journal of the American Academy of Dermatology
|July 1, 1995
Summary
Neonatal lupus erythematosus (NLE) can present with telangiectases, which are vascular lesions, even without prior skin inflammation. These early NLE signs can appear in sun-protected areas.
Area of Science:
- Dermatology
- Neonatology
- Immunology
Background:
- Neonatal lupus erythematosus (NLE) is an autoimmune condition affecting newborns.
- Persistent telangiectases are known NLE manifestations, typically in areas with prior dermatitis.
- The appearance of vascular lesions without preceding inflammation in NLE was previously unreported.
Observation:
- This study highlights a novel presentation of cutaneous NLE.
- Angiomatous or matlike telangiectases were observed in infants without antecedent or concurrent dermatitis.
- Seven infants with primary or early NLE featured telangiectatic macules or angiomatous papules.
Findings:
- Five infants showed telangiectasia development without prior or concurrent inflammatory lesions.
- Vulvar or inguinal angiomatous papules were noted in four infants.
- These vascular findings occurred independently of classic "lupus dermatitis."
Implications:
- Telangiectases can be an initial presenting sign of NLE.
- These vascular lesions may appear in sun-protected body sites.
- NLE diagnosis should consider telangiectases even without concurrent dermatitis.
