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[Sleep apnea syndrome]
K Tatsumi1, S Masuyama, H Kimura
1Department of Chest Medicine, School of Medicine, Chiba University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi
|December 1, 1994
Summary
Excessive daytime sleepiness (EDS) may stem from sleep apnea syndrome. While sleep disturbance and blood gas changes may contribute to EDS, hypoxemia is unlikely to cause daytime hypertension.
Area of Science:
- Cardiopulmonary physiology
- Sleep medicine
Context:
- Sleep apnea syndrome is linked to excessive daytime sleepiness (EDS), daytime hypertension, and pulmonary hypertension (PH).
- Intermittent upper airway obstruction during sleep can cause transient, severe elevations in systemic and pulmonary arterial pressures.
Purpose:
- To investigate the contribution of daytime and sleep hypoxemia to EDS, daytime hypertension, and PH in patients with sleep apnea syndrome.
Summary:
- Sleep disturbance and blood gas alterations during wakefulness and sleep may contribute to EDS.
- Hypoxemia during wakefulness and sleep does not appear to be involved in daytime hypertension.
- Mean resting pulmonary arterial pressure correlates with daytime PO2, PCO2, body mass index, FVC, and FEV1.0%.
Impact:
- Findings suggest that sleep disturbance and blood gas changes are potential factors in EDS.
- Cardiopulmonary hemodynamic function may improve with appropriate treatment for sleep apnea syndrome.