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[The Clark ("dysplastic") nevus in Mexico]

M Magaña1

  • 1Facultad de Medicina, Universidad Nacional Autónoma de México, Clínica de Dermatología Pediátrica, Hospital General de México.

Gaceta Medica De Mexico
|September 1, 1994
PubMed
Summary

Clark's nevus is uncommon in Mexico, primarily affecting fair-skinned individuals. While recognizable by clinicians, associated melanoma cases were noted, but dysplastic nevus syndrome appears rare in the mestizo population.

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Area of Science:

  • Dermatology
  • Pathology
  • Epidemiology

Background:

  • Clark's nevus (melanocytic nevus) is a type of mole.
  • Understanding its prevalence and clinical presentation is important for early detection of melanoma.
  • The mixed (mestizo) population in Mexico presents unique demographic considerations.

Purpose of the Study:

  • To determine the prevalence of Clark's nevus in Mexico City.
  • To describe the clinical features of Clark's nevus in the Mexican population.
  • To assess the association between Clark's nevus and melanoma, and the occurrence of dysplastic nevus syndrome.

Main Methods:

  • Analysis of 100 Clark's nevus cases over 37 months.
  • Data collected from three pathology laboratories in Mexico City.
  • Review of clinical features and patient demographics.

Main Results:

  • Clark's nevus is not highly common but is observed predominantly in fair-skinned individuals.
  • The condition is recognizable by trained clinicians.
  • Four cases of Clark's nevus were associated with melanoma; no cases met criteria for dysplastic nevus syndrome.

Conclusions:

  • Clark's nevus has a low prevalence in the studied Mexican population.
  • Fair skin is a key clinical feature.
  • Dysplastic nevus syndrome may be infrequent in Mexico's mixed population, warranting further investigation.

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