Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sympathetic Signaling01:31

Sympathetic Signaling

2.2K
Sympathetic signaling, a vital part of the autonomic nervous system, plays a crucial role in mobilizing the body's resources in response to stress or emergencies. It involves the transmission of nerve impulses from sympathetic preganglionic fibers to postganglionic fibers. This results in the release of specific neurotransmitters and activation of adrenergic receptors.
Sympathetic preganglionic fibers release the neurotransmitter acetylcholine (ACh) onto the ganglionic neurons in the...
2.2K
Sympathetic Activation01:16

Sympathetic Activation

6.7K
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
6.7K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla01:27

Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla

2.6K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
2.6K
Sympathetic Pathways: Sympathetic Chain Ganglia01:20

Sympathetic Pathways: Sympathetic Chain Ganglia

5.9K
The sympathetic chain ganglia, also known as the sympathetic trunk ganglia or paravertebral ganglia, are a series of ganglia located bilaterally on either side of the spinal column. These ganglia serve as relay stations for the sympathetic nervous system. Preganglionic neurons originating in the spinal cord project their axons to the sympathetic chain ganglia. Within the ganglia, these preganglionic fibers synapse with postganglionic neurons.The postganglionic neurons of the sympathetic trunk...
5.9K
The Sympathetic Nervous System01:25

The Sympathetic Nervous System

103.3K
Overview
103.3K
Sympathetic Division of the ANS01:19

Sympathetic Division of the ANS

3.3K
The sympathetic division of the autonomic nervous system (ANS) plays a crucial role in preparing the body for stress, physical activity, and increased energy demands. This division activates the "fight-or-flight" response, enabling individuals to respond effectively to challenging situations.
Originating in the thoracic and lumbar spinal cord segments, the preganglionic fibers of the sympathetic division exit the spinal cord through the white ramus communicans. They then enter the...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insights from Magnetic Evoked Field Analysis in Patients with Wilson's Disease.

Neurology India·2022
Same author

Has physical examination superannuated? …Not yet!

Neurology India·2020
Same author

Post-stroke Gait Analysis in Rehabilitation Set-up: Observational or Instrumental!

Neurology India·2019
Same author

Motor recovery and therapeutic interventions.

Neurology India·2018
Same author

Intravenous with intrathecal interferon in subacute sclerosing panencephalitis.

Neurology India·2018
Same author

Acute inflammatory demyelinating polyradiculopathy in children : a clinical and electrophysiological study.

Neurology India·2018
Same journal

Comment on "Efficacy and safety of conventional immunosuppressant therapies in elderly patients with Neuromyelitis optica spectrum disorder: A target trial emulation study".

Journal of the neurological sciences·2026
Same journal

Increasing incidence of varicella-zoster virus meningitis in Japan, 2011-2022.

Journal of the neurological sciences·2026
Same journal

Comment on "Excellent agreement between automated deep learning-based and manual diffusion-weighted imaging infarct volume measurements in hyperacute stroke".

Journal of the neurological sciences·2026
Same journal

Shifting from alteplase to tenecteplase in acute ischemic stroke: Progress, promise, and perils.

Journal of the neurological sciences·2026
Same journal

Time-resolved GluCEST MRI of acute glutamate-related signal changes following kainic acid administration.

Journal of the neurological sciences·2026
Same journal

Comment on "Real-world timing of early anticoagulation therapy in intracerebral hemorrhage patients with atrial fibrillation".

Journal of the neurological sciences·2026
See all related articles

Related Experiment Video

Updated: Jan 26, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
06:30

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats

Published on: September 11, 2018

8.2K

Sympathetic skin response: a decade later

G R Arunodaya1, A B Taly

  • 1Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, India.

Journal of the Neurological Sciences
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Sympathetic skin response (SSR) testing offers a simple way to evaluate autonomic nervous system function. However, a clear consensus on abnormal SSR changes is still needed for reliable clinical decisions.

More Related Videos

Methods for Skin Wounding and Assays for Wound Responses in C. elegans
09:06

Methods for Skin Wounding and Assays for Wound Responses in C. elegans

Published on: December 3, 2014

10.8K
Protocol for Culturing Sympathetic Neurons from Rat Superior Cervical Ganglia SCG
11:49

Protocol for Culturing Sympathetic Neurons from Rat Superior Cervical Ganglia SCG

Published on: January 29, 2009

23.9K

Related Experiment Videos

Last Updated: Jan 26, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
06:30

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats

Published on: September 11, 2018

8.2K
Methods for Skin Wounding and Assays for Wound Responses in C. elegans
09:06

Methods for Skin Wounding and Assays for Wound Responses in C. elegans

Published on: December 3, 2014

10.8K
Protocol for Culturing Sympathetic Neurons from Rat Superior Cervical Ganglia SCG
11:49

Protocol for Culturing Sympathetic Neurons from Rat Superior Cervical Ganglia SCG

Published on: January 29, 2009

23.9K

Area of Science:

  • Neuroscience
  • Autonomic Nervous System Physiology
  • Electrophysiology

Background:

  • The sympathetic skin response (SSR) is a well-established electrophysiological test assessing autonomic nervous system function.
  • It involves a polysynaptic reflex with diverse inputs and a common sympathetic efferent pathway to sweat glands.
  • SSR has been applied to diagnose various peripheral and central nervous system disorders.

Purpose of the Study:

  • To critically evaluate the methodology and clinical utility of SSR.
  • To review the anatomic substrates and changes in SSR across different diseases.
  • To correlate SSR findings with clinical features of dysautonomia and other electrophysiological parameters.

Main Methods:

  • Review of existing literature on SSR methodology, application, and interpretation.
  • Analysis of studies correlating SSR with clinical manifestations of dysautonomia.
  • Comparison of SSR with other bedside autonomic function tests and electrophysiological measures.

Main Results:

  • SSR is a simple and reproducible test, valuable in assessing autonomic function.
  • Despite widespread use, consensus on abnormal SSR criteria remains elusive.
  • Sole reliance on SSR for prognostication or treatment decisions is considered impracticable.

Conclusions:

  • SSR is a useful bedside test for autonomic dysfunction but requires standardized interpretation.
  • A comprehensive battery of autonomic function tests is necessary for accurate diagnosis and management.
  • Further research is needed to establish definitive criteria for abnormal SSR findings.