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Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Endocarditis-related cerebral aneurysms: radiologic changes with treatment
P Corr1, M Wright, L C Handler
1Department of Neuroradiology, Groote Schuur Hospital, Cape Town, South Africa.
Antibiotic therapy can resolve mycotic aneurysms, but follow-up angiography is crucial for monitoring treatment response and detecting changes in aneurysm size or new formations.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Mycotic aneurysms, often linked to infective endocarditis, pose significant risks including hemorrhage and stroke.
- Early diagnosis and effective treatment are vital for improving patient outcomes.
Purpose of the Study:
- To evaluate the effectiveness of antibiotic therapy in treating mycotic aneurysms.
- To correlate treatment response with patient outcomes.
Main Methods:
- Retrospective review of clinical data, CT scans, and serial cerebral angiograms.
- Analysis of 14 patients diagnosed with infective endocarditis and related aneurysms over a 10-year period.
Main Results:
- Antibiotic treatment led to complete resolution of 33% of mycotic aneurysms.
- 33% of aneurysms showed no change in size, 17% decreased, and 17% increased.
- 50% of patients achieved complete recovery, while others experienced deficits or death from rebleeding.
Conclusions:
- Follow-up angiography is essential for assessing antibiotic therapy response in mycotic aneurysms.
- Angiography helps identify aneurysms requiring further intervention due to lack of response or enlargement.
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