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Related Experiment Videos

Relation between collateral flow assessed by Doppler guide wire and angiographic collateral grades

T Yamada1, M Okamoto, T Sueda

  • 1Department of Cardiology, Hiroshima Prefectural Hiroshima Hospital, Japan.

American Heart Journal
|July 1, 1995
PubMed
Summary

Doppler guide wire assessment of coronary collateral flow velocity reveals a strong correlation between flow duration and angiographic collateral grade in angina pectoris patients. This method aids in evaluating collateral function.

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Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Hemodynamics

Background:

  • Coronary collateral circulation plays a vital role in myocardial perfusion during ischemia.
  • Assessing collateral function is crucial for predicting outcomes in patients with coronary artery disease.

Purpose of the Study:

  • To investigate the relationship between angiographic collateral grade (Rentrop's classification) and collateral flow velocity patterns.
  • To determine the utility of Doppler guide wire measurements in assessing collateral function.

Main Methods:

  • Doppler guide wire was used to measure collateral flow velocity during balloon occlusion in 43 angina pectoris patients.
  • Collateral flow direction and velocity parameters were analyzed.
  • Correlation with Rentrop's angiographic collateral grade was assessed.

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Main Results:

  • Collateral flow was detected in 21 patients; 6 had no visible collaterals angiographically prior to intervention.
  • Peak collateral flow velocity did not correlate with angiographic grade.
  • Collateral flow duration ratio and peak velocity integral correlated significantly with angiographic grades (p < 0.0005 and p < 0.05, respectively).
  • Unidirectional and longer duration collateral flow patterns were associated with reduced ischemic signs.

Conclusions:

  • Collateral flow duration and peak velocity integral measured by Doppler guide wire are valuable indicators of collateral function.
  • Doppler guide wire assessment provides a functional correlate to angiographic collateral grading.
  • This technique may enhance the evaluation of collateral status in patients with coronary artery disease.