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Aspergillus peritonitis: therapy, survival, and return to peritoneal dialysis

A M Miles1, R H Barth

  • 1Renal Division, Veterans Affairs Medical Center, Brooklyn, NY 11209, USA.

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|July 1, 1995
PubMed

Insights

Aspergillus peritonitis in peritoneal dialysis patients is rare and deadly. Successful treatment with antifungal drugs and catheter removal allowed one patient to resume peritoneal dialysis, suggesting early intervention improves outcomes.

Area of Science:

  • Nephrology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal peritonitis, particularly Aspergillus species, presents a rare but severe complication in peritoneal dialysis (PD) patients.
  • Cases of Aspergillus peritonitis are associated with high mortality and significant challenges in resuming PD therapy.

Observation:

  • A case of Aspergillus niger peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis (CAPD) is presented.
  • The patient was treated with intravenous amphotericin B and removal of the peritoneal dialysis catheter.

Findings:

  • The patient successfully recovered and was able to resume CAPD after 2 months.
  • Peritoneal transport function remained stable 1 year after the resumption of CAPD.

Implications:

  • Early diagnosis and aggressive management, including antifungal therapy and catheter management, are crucial for Aspergillus peritonitis.
  • Successful treatment may enable patients to return to and maintain long-term peritoneal dialysis, improving quality of life.

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