Related Experiment Video
Updated: Jul 25, 2026

04:25
Local Hyperthermia for Warts Treatment
Published on: November 8, 2024
Recurrent palmoplantar hidradenitis in children
L G Rabinowitz1, M L Cintra, A F Hood
1Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA.
Archives of Dermatology
|July 1, 1995
Summary
Recurrent palmoplantar hidradenitis presents as tender, red nodules on the feet and sometimes hands in children. This condition, characterized by neutrophilic eccrine infiltrates, typically resolves on its own.
Area of Science:
- Dermatology
- Pediatric Dermatology
- Dermatopathology
Background:
- Reports describe tender, erythematous plantar nodules in children with diverse histologic findings.
- Idiopathic plantar hidradenitis (neutrophilic eccrine hidradenitis in children) is a recently described entity with specific histopathologic features.
- Distinguishing between similar-appearing pediatric plantar lesions is clinically relevant.
Observation:
- Two pediatric cases of recurrent palmoplantar nodules with unique histopathologic findings are presented.
- Unlike typical idiopathic plantar hidradenitis, palm and sole involvement was observed.
- Lesions were self-limited and recurrent, with one case associated with low-grade fever.
Findings:
- Histopathologic analysis revealed dense neutrophilic infiltrates localized to eccrine units in both patients.
- Clinical presentation included tender, erythematous nodules on the palms and soles.
- The findings align with, yet expand upon, the description of idiopathic plantar hidradenitis.
Implications:
- The condition shares clinical and histologic similarities with idiopathic plantar hidradenitis.
- Recurrence and potential palm involvement suggest a broader classification.
- The term 'recurrent palmoplantar hidradenitis' is proposed to encompass these features.
Related Concept Videos
Papillary Dermis
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Accessory Structures of the Skin: Sebaceous Glands
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Chronic Pancreatitis I: Introduction
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Chickenpox
Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
Chronic Pancreatitis I: Introduction
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...