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Glucagon-induced small intestinal hypotonia demonstrating bleeding lymphoma
Gastrointestinal Radiology
|January 30, 1979
Summary
Glucagon-induced hypotonic small bowel examination identified an ulcerated jejunal mass missed by prior imaging. This rapid, side-effect-free procedure may aid in diagnosing obscure gastrointestinal bleeding.
Area of Science:
- Gastroenterology
- Diagnostic Imaging
- Oncology
Background:
- Melena evaluation often requires advanced imaging to localize gastrointestinal bleeding.
- Conventional small bowel imaging techniques can be limited in detecting subtle lesions.
Observation:
- A patient with melena underwent a glucagon-induced hypotonic small intestine examination.
- Previous investigations including gastrointestinal series, small intestinal series, barium enemas, and arteriography failed to identify the bleeding source.
Findings:
- The glucagon-induced hypotonic examination revealed a small, ulcerated mass in the jejunum.
- Surgical exploration confirmed three ulcerated lymphomatous lesions in the jejunum.
Implications:
- Glucagon-induced hypotonic small intestine examination offers a rapid, well-tolerated diagnostic adjunct.
- This technique may improve the detection rate of obscure gastrointestinal bleeding sources, particularly lymphoma.