Related Experiment Video
Updated: Aug 18, 2026
Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
Published on: October 16, 2014
Necrotizing (malignant) external otitis: prospective comparison of CT and MR imaging in diagnosis and follow-up
J R Grandis1, H D Curtin, V L Yu
1Department of Otolaryngology, University of Pittsburgh, Montefiore University Hospital, PA 15213, USA.
Purpose:
To compare computed tomography (CT) and magnetic resonance (MR) imaging in the diagnosis and follow-up of necrotizing external otitis.
Materials And Methods:
CT and MR imaging were performed in seven patients at diagnosis and at 6 and 12 months after initiation of therapy. Imaging findings were compared and correlated with the clinical course of the disease.
Results:
Cortical bone erosion was best seen on CT scans (n = 5 vs n = 0 on MR images) and failed to normalize with cure. Subtemporal soft-tissue abnormalities (n = 7 with both modalities) were better appreciated with MR imaging and had low signal intensity on T1- and T2-weighted images. Soft-tissue changes improved but did not disappear completely with treatment.
Conclusion:
CT is preferred at initial diagnosis, as small cortical erosions are better seen. Either modality can be used to follow up soft-tissue evolution. MR imaging may be better for evaluation and follow-up of meningeal enhancement and changes within the osseous medullary cavity.
