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Hyperreninemia and secondary hyperaldosteronism in pheochromocytomas
The Journal of Pediatrics
|February 1, 1979
Summary
Pheochromocytoma can cause hyperreninemia and secondary hyperaldosteronism in hypertensive adolescents. Early diagnosis of this surgically correctable cause of hypertension is crucial.
Area of Science:
- Endocrinology
- Nephrology
- Pediatric Hypertension
Background:
- Hypertension diagnosis requires identifying surgically correctable causes.
- Elevated plasma renin activity suggests renovascular or renal origins.
Observation:
- Two adolescent patients presented with hypertension and hyperreninemia.
- Pheochromocytoma was identified as the cause of hyperreninemia in both cases.
Findings:
- Pheochromocytoma can manifest as a cause of secondary hyperreninemic hypertension.
- Secondary hyperaldosteronism was observed in association with pheochromocytoma.
Implications:
- Pheochromocytoma should be considered in the differential diagnosis of hyperreninemic hypertension in adolescents.
- Identifying and surgically correcting pheochromocytoma can resolve hypertension.