Developmental changes in mRNA encoding cardiac Na+/H+ exchanger (NHE-1) in rabbit

F Chen1, J M Jarmakani, C Van Dop

  • 1Division of Pediatric Cardiology, University of California, Los Angeles 90095-1752, USA.

Summary

Newborn rabbit hearts show faster recovery from acidosis due to higher Na+/H+ exchanger-1 (NHE-1) activity. NHE-1 mRNA levels are significantly higher in fetal and newborn hearts compared to adult hearts, explaining this difference.

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