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Updated: Aug 2, 2026
13:13
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Neonatal jaundice in Zaria, Nigeria--a second prospective study
H Ahmed1, A M Yukubu, R G Hendrickse
1Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
West African Journal of Medicine
|January 1, 1995
Summary
Neonatal jaundice is common in Nigeria, with significant hyperbilirubinaemia and kernicterus occurring more frequently in outborn infants. Septicaemia and G6PD deficiency were the primary causes.
Area of Science:
- Neonatal Medicine
- Pediatrics
- Public Health
Background:
- Neonatal jaundice is a prevalent condition in newborns.
- Significant hyperbilirubinaemia and kernicterus pose serious health risks.
- Understanding etiological factors is crucial for effective management.
Purpose of the Study:
- To investigate the incidence and severity of neonatal jaundice in Zaria, Nigeria.
- To identify the primary etiological factors contributing to neonatal jaundice.
- To compare outcomes between hospital-born and outborn neonates.
Main Methods:
- A double prospective study involving 587 followed-up neonates and 279 admitted through the Emergency Paediatric Unit.
- Clinical assessment of jaundice and measurement of serum bilirubin levels.
- Comparison of jaundice incidence, severity, and etiological factors between different birth settings.
Main Results:
- 16.9% of followed-up neonates and 25% of EPU admissions were jaundiced.
- Higher incidence of severe hyperbilirubinaemia and kernicterus (20.3%) in outborn neonates compared to hospital-born (2.6%).
- Septicaemia (50%) and G6PD deficiency (40%) were the leading causes; Rh-incompatibility was not observed.
Conclusions:
- Neonatal jaundice poses a significant challenge in Zaria, with outborn infants at higher risk.
- Prompt identification and management of hyperbilirubinaemia are essential to prevent kernicterus.
- Septicaemia and G6PD deficiency are key etiological factors requiring targeted interventions.
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