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Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
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Recognition and control of neisserial infection by antibody and complement
1Dept of Laboratory Medicine, University of California, San Francisco 94121, USA.
Trends in Microbiology
|May 1, 1995
Abstract:
Immunity to neisserial infection involves complex interactions between antibody, complement and bacterial cell-surface molecules. Neisseria species express polysaccharide and glycolipid membrane components, which downregulate complement activation. The pathogenic potential of Neisseria depends on evasion of the complement cascade.
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