[Function of acoustic analyzer in multiple sclerosis in exacerbation]

Area of Science:

• Neuroscience
• Audiology
• Otolaryngology

Context:

• Aggravated multiple sclerosis (MS) presents complex neurological challenges.
• Auditory system involvement in MS is often underdiagnosed.
• Comprehensive audiological assessment is crucial for MS patients.

Purpose:

• To investigate the prevalence and characteristics of auditory system dysfunction in patients with aggravated multiple sclerosis.
• To evaluate the impact of sorption detoxication therapy on auditory function in MS patients.
• To explore the relationship between subjective/neurological improvements and objective acoustic criteria post-therapy.

Summary:

• Audiometric examinations, including pure-tone, speech, and evoked potentials, were performed on 51 aggravated MS patients.
• Acoustic analyzer dysfunction, especially sound laterality, was found in a significant percentage of patients (42-83%).
• Hearing impairment predominantly affected the brain stem (68%), with occasional cochlear involvement (15%).
• Sorption detoxication therapy yielded subjective and neurological improvements in 100% of patients, but only 59% showed acoustic improvement.
• The discrepancy between subjective and acoustic responses suggests subclinical auditory symptoms with potential prognostic implications.

Impact:

• Highlights the high incidence of auditory pathway dysfunction in MS, often subclinical.
• Suggests that persistent auditory deficits post-therapy may serve as a prognostic indicator in MS.
• Emphasizes the need for routine audiological evaluations in the management of multiple sclerosis.