[Use of clofelin as an anesthetic and component of neurovegetative defense in ENT oncologic surgery]

Metabolism indices (blood sugar, lactic acid, pyruvic acid) and hemodynamics (mean arterial pressure, 1-hour diuresis) were measured in 41 hypertensive subjects undergoing resection or removal of the larynx for cancer under endotracheal anesthesia through tracheostoma. 18 patients of group 1 received calypsol anesthesia, whereas 23 patients of group 2 received combination of calypsol with clofelin. Croup 2 patients benefited more because clofelin potentiated the analgetic effect of calypsol, intensified neurovegetative block, promoted more rapid recovery of normal respiration, prolonged analgetic effect in postoperative period.