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Corneal perforation in a premature infant
B M Zagelbaum1, E M Stroh, H D Perry
1Department of Ophthalmology, North Shore University Hospital, Manhasset, NY 11030, USA.
Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|March 1, 1995
Summary
Corneal perforation is a rare but serious risk in premature infants with epithelial defects. Early recognition and intervention are crucial for managing this sight-threatening condition.
Area of Science:
- Ophthalmology
- Neonatology
- Pediatric Surgery
Background:
- Corneal perforation is a rare complication in premature infants.
- Limited literature exists on this specific condition.
Observation:
- Identical twins born at 30 weeks gestation presented with distinct corneal issues.
- One twin experienced corneal epithelial defect, infiltration, and perforation, necessitating emergency penetrating keratoplasty.
- The other twin developed progressive corneal opacity, requiring lamellar keratectomy.
Findings:
- The twin undergoing penetrating keratoplasty developed absolute glaucoma and buphthalmos, ultimately requiring enucleation.
- Histopathological examination of the lamellar keratectomy specimen revealed a corneal dermoid in the second twin.
Implications:
- Clinicians should maintain a high index of suspicion for spontaneous corneal perforation in premature infants with epithelial defects.
- Prompt diagnosis and management are essential to prevent severe visual impairment and potential loss of the eye.
- Corneal dermoids should be considered in the differential diagnosis of corneal opacities in neonates.