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Cerebral phaeohyphomycosis complicated with brain abscess: a case report
J F Lirng1, R D Tien, A K Osumi
1Department of Radiology, National Yang-Ming University, Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed
|June 1, 1995
Summary
Cerebral phaeohyphomycosis, a rare brain infection, was treated by surgically removing the abscess and using antifungal drugs. This approach led to a successful recovery for the patient with Xylohypha bantiana infection.
Area of Science:
- Mycology
- Neurology
- Infectious Diseases
Background:
- Cerebral phaeohyphomycosis is a rare infection of the brain caused by pigmented fungi.
- It typically manifests as a brain abscess, posing diagnostic and therapeutic challenges.
Observation:
- A patient presented with seizures, and MRI revealed a ring-enhancing lesion with edema.
- The lesion, caused by Xylohypha bantiana, recurred after initial surgical removal.
Findings:
- Diagnosis was confirmed by fungal cultivation and histopathology of Xylohypha bantiana.
- Combined therapy of surgical excision and antifungal drugs (5-flucytosine, itraconazole) led to a favorable outcome.
Implications:
- Complete surgical resection of the brain abscess is crucial for managing cerebral phaeohyphomycosis.
- Aggressive antifungal treatment alongside surgery offers the best prognosis for this rare fungal infection.
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