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Lung tumors derived from ectopic tissues

A M Marchevsky1

  • 1Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Seminars in Diagnostic Pathology
|May 1, 1995
PubMed
Summary
This summary is machine-generated.

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Ectopic tissues in the lung are rare, manifesting as choristomas or neoplasms. This review discusses the clinicopathological features of these unusual intrapulmonary findings.

Area of Science:

  • Pulmonology
  • Pathology
  • Oncology

Background:

  • Ectopic tissues, such as endometriosis, thyroid, pancreas, adrenal, and neurological tissue, are infrequently found within the lung.
  • Choristomas represent rare developmental anomalies arising from these heterotopic tissues, forming masses of histologically normal but misplaced tissue.
  • Intrapulmonary neoplasms can also rarely originate from ectopic tissues.

Purpose of the Study:

  • To review and discuss the clinicopathological features of rare intrapulmonary neoplasms and choristomas derived from ectopic tissues.
  • To consolidate information on the diverse origins and presentations of these unusual lung conditions.

Main Methods:

  • Literature review of ectopic tissues and associated neoplasms in the lung.
  • Analysis of clinicopathological characteristics of reported cases.

Related Experiment Videos

  • Categorization of neoplasms based on their ectopic tissue of origin.

    • Main Results:

    • Ectopic tissues in the lung are diverse, including endometriosis, thyroid, pancreas, adrenal, and neural tissue.
    • Associated choristomas are benign developmental anomalies.
    • Rare neoplasms identified include malignant melanoma, thymoma, meningioma, glomus tumor, germ cell neoplasms (choriocarcinoma, teratoma), and ependymoma.

    Conclusions:

    • Ectopic tissues in the lung are a rare phenomenon, leading to both benign choristomas and various malignant neoplasms.
    • Understanding the clinicopathological features of these unusual entities is crucial for accurate diagnosis and management.
    • Further research into the pathogenesis and optimal treatment strategies for these rare pulmonary conditions is warranted.