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Tumoral multiple sclerosis of the cerebellum in a child

J A Rusin1, L G Vezina, W M Chadduck

  • 1Department of Diagnostic Imaging and Radiology, Children's National Medical Center, Washington, DC 20010, USA.

Insights

We report a rare case of tumoral multiple sclerosis in an 11-year-old girl. This condition can present as a posterior fossa mass and show ring enhancement on MRI scans.

Area of Science:

  • Neurology
  • Radiology
  • Pediatric Neurology

Background:

  • Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system.
  • Tumoral MS is a rare variant characterized by a tumefactive demyelinating lesion that mimics a brain tumor.
  • Posterior fossa lesions are less common in MS but can occur.

Observation:

  • An 11-year-old girl presented with symptoms suggestive of a posterior fossa mass.
  • Magnetic resonance imaging (MRI) revealed a lesion in the cerebellum.
  • Typical white matter lesions were also noted on T2-weighted images.

Findings:

  • The cerebellar lesion was diagnosed as tumoral multiple sclerosis.
  • This case highlights that tumoral MS can occur in the posterior fossa.
  • The lesion demonstrated characteristic ring enhancement on MRI, a feature sometimes seen in tumoral MS.

Implications:

  • Tumoral multiple sclerosis should be considered in the differential diagnosis of posterior fossa mass lesions, especially when associated with typical white matter MS lesions.
  • Recognizing ring enhancement on MRI can aid in the diagnosis of tumoral MS.
  • This case expands the understanding of the diverse presentations of MS in pediatric patients.

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