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Tumoral multiple sclerosis of the cerebellum in a child
J A Rusin1, L G Vezina, W M Chadduck
1Department of Diagnostic Imaging and Radiology, Children's National Medical Center, Washington, DC 20010, USA.
Insights
We report a rare case of tumoral multiple sclerosis in an 11-year-old girl. This condition can present as a posterior fossa mass and show ring enhancement on MRI scans.
Area of Science:
- Neurology
- Radiology
- Pediatric Neurology
Background:
- Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system.
- Tumoral MS is a rare variant characterized by a tumefactive demyelinating lesion that mimics a brain tumor.
- Posterior fossa lesions are less common in MS but can occur.
Observation:
- An 11-year-old girl presented with symptoms suggestive of a posterior fossa mass.
- Magnetic resonance imaging (MRI) revealed a lesion in the cerebellum.
- Typical white matter lesions were also noted on T2-weighted images.
Findings:
- The cerebellar lesion was diagnosed as tumoral multiple sclerosis.
- This case highlights that tumoral MS can occur in the posterior fossa.
- The lesion demonstrated characteristic ring enhancement on MRI, a feature sometimes seen in tumoral MS.
Implications:
- Tumoral multiple sclerosis should be considered in the differential diagnosis of posterior fossa mass lesions, especially when associated with typical white matter MS lesions.
- Recognizing ring enhancement on MRI can aid in the diagnosis of tumoral MS.
- This case expands the understanding of the diverse presentations of MS in pediatric patients.
Abstract:
We present a case of cerebellar tumoral multiple sclerosis in an 11-year-old girl and emphasize these two features: (1) Tumoral multiple sclerosis can occur within the posterior fossa and should be strongly considered in the differential diagnosis of mass lesions of the posterior fossa when typical white matter lesions are seen on T2-weighted images. (2) Tumoral multiple sclerosis can demonstrate ring enhancement on MR.